Sometimes you may face with situation when ISE Application Server fails to start and you may see the following situation when checking show application status ise output:
Usual tricks like application stop ise followed by application start ise safe or application reset-config ise won't help. What's next? Re-image? No, not yet. No matter how many times you reload the ISE or wipe/redeploy your instance, state will persist.
So, how to fix? First of all, check interface status first with show interface and you may see that interface does not have address assigned for some reason despite that it is presented in the configuration and interface is not shutted down:
Note that for me it happened only in case if ISE connected to network type "Cloud". So your fix will typical "shutdown/no shutdown":
After this, just execute usual application start ise and ISE will start normally:
Finally check the status again after few couple of minutes with command show application status ise and you will see that ISE processes are running:
I'll be glad to know if it helped somebody, leave comments please.